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Secretariat#    !  #: Dt#:  Y #  Dt ) )% O %O # "AE #Dt #DtՇ #X$XDtDistr.  % P GENERAL%P "(US  SU , (ST/SG/AC.10/1998/,x,-INF.xx-*x*,+INF+,"&UK  US  &22July1998Original:ENGLISH H>-vv  H ,"H ,/%#H   /Q֛RA;G) QxdCEQPxAߛ+қTRW\6&A43'6&A43'T# X$X$XX' #X$X$X X#Dt$XXs #72DtUKUS.,Aga#Dt278#X$XDtAGEMdgemmndaitem2(c)#Dt$XX#72Dt9#UN/CETDG/20/INF.2818# 7227## Dt2 7# X$X DtUS.,UK.,WԈ   # Dt$X Xv# X$X DtX$X$X X COMMITTEEOFEXPERTSONTHETRANSPORTOFDANGEROUSGOODS(Twentiethsession,Geneva,716Decemberl998,agendaitem2((d()c)))# X$X$XX(#ZX/K&X$X X#Za(&XZX/K #Z?*?(Za@ 5OTHERDRAFTAMENDMENTS #Za(*?Z?~#ZZ,(Za# X-,ZZ<#ZZ,- XԈ   #Za(,ZZ#Z?*?(Za @mm5Comments #Za(*?Z?ކ#Z?*?(Za  # ?hB.?*?Z?-#  "?S-0?.? ?hB onModificationofentriescontainingtheword inhibited   # ?p,?(?Z?~##"f(?"?~ #"^""f UKUS.," "Coppersulphate,solidorsolution!! #"f""^# US.,UK.,{ "?~(?"fZ?~(?,? ?p  #(#ST/SG/AC # ?hB.?0?"?S-Y#  Z?*?.? ?hB  #Za(*?Z?#  Z?*?(Za .10/1998/46$($%񀄀%Germany)#Za(*?Z?=#Z?*?(Za# ?hB.?*?Z?#Z?*?.? ?hB     ?+ 4 <DL!X?  <( 4 <DL!X<# ?hB.?*?Z?"## Dt.? ?hB# X$X Dt TransmittedbytheExpertfromtheUnitedStatesofAmerica  E  ''  X$X$X XC $#C&CommentsonGermansproposalonCopperSulphate&ByU.S.A.̀ $ TheExpertfromUnitedStatesofAmericahasreviewedtheproposalfromGermanyonCopperSulphateanddoesnotsupporttheproposalforthefollowingreasons:̜1. $ Theassertionthatcoppersulphate,solidsandsolutions,ha.d./s/ddDpreviouslyDbeenregulatedunderUN3010  isincorrect.UN3010112,2CopperBasedPesticides334,40are00is0forpesticidesthatmeettheDivision6.1criteria5(5i.e.6,69779::toxicitydatabasedonanimaltesting8)8.;;<<Inthiscontext==>,>coppersulphatedoesnotmeettheclassificationcriteriaofDiv?.?@is@A@s@ABionB6.1asindicatedbydatacitedinCGermanysCCyourCpaper.̜2. $ TheUNRecommendationsEpreviouslyincludedEEusedtohaveEapesticidestable.Thattablewasreviewed i byexpertsFfromtheFFinFGWHO(GWorldHealthOrganizationH)HI(WHO)IanddidnotJincludeJJspecificallymentionJcoppersulphateasbeKenKLingLaDivM.MNisionN6.1pesticide.̀3. $ TheGermanproposalcitedOafewOliteraturePsourcestoPYindicatingYYsupportYQQYRingRtheclaimYthatSbyhumanexperienceScoppersulphateTisTThasTUTbeenshTUbeenVprovenVVtobeVtoxicW T byhumanexperienceW.TheexpertfromtheUnitedStateshasWehaveZreviewedZZcheckedZdatafromtheAmericanAssociationof[PoisonControlCenters([]AA]PCC\)\forthelasttenyears.Therehavebeenabout800casesreportedinvolvingcopper^/^_and_coppersalts..Ofthosetherewere5deathsand18`cases`withlife-threateningeffects.cAllofthedeathswereadultsccOfthecd5ddcfivecdcdeaths,caacb;bce4eefoureweresuicideswithingestionofcoppersulphatefwithotherstuffsfgandotherghmaterialshhgchemicalsghm,andtheotherml.Thek5thdeathklkiotherdeathikdeathjinvolvedajilastoneijwasaj69rrssyearnnpoopqqoldwhoaccidentallyinhaledcopperchlorideandBenomyl.uDatatistuvDatavwvsvwxisnotreadilyavailableforthexzxotherxzxcasesxywithlifethreateningeffects.ytaretunoteasilyaccessibleontheothermajoreffectcases.uTheGermanproposalcitedanestimatedfataldoseofabout140mg/kgbutdidnotelaborateonhowthisfigure{i{|wa|sderived.̜4. $ Coppersulphateisaknownemetic}s}(~agentthat~~indu~~ice~ces~causing~vomiting)thusitlimitstheamountthatcanbe Q'$' ingestedbyintothebodytoandcausingetoxiceffects. $ TInconclusion,tTAsTtheGermanysproposalisbasedonanestimatedtoxicityderivedfromonunspecifiedhumaneexperience.T,t.TheExpertfromtheUnitedStatesbelievesisoftheopinionthatmorespecificdatacitationandestimationoftoxicitybasedonhuanmanexperienceshouldbebasedonhumanexperienceisarerequiredtoclassifycoppersulphateinDiv.ision6.11assuggeproposedbyGermany.asproposedbyGermany..# X$X$XXm#YYX +(), XYYXXYY@(5_______X@@-X